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have a digenetic everyday living cycle, involving a motile, extracellular promastigote phase that parasitizes the alimentary tract of a sandfly vector and an immotile amastigote phase that survives and replicates from the phagolysosomes of mononuclear phagocytes [2,three]. Aside from humans, primary hosts of Leishmaniaand in vivo antileishmanial ef